بررسی نقش سابقه مصرف سیگار در تهوع و استفراغ بعد از عمل

Aims and Background: Untreated, one third of patients who undergo surgery will have postoperative nausea and vomiting (PONV). In the meanwhile, active smoking can protect against the development of this complication. We investigated the role of cigarette smoking history on postoperative nausea and vomiting. Materials and Methods: In a prospective analytical study, 50 cigarette smokers and nonsmoker patients, candidate for transurethral lithotripsy under general anesthesia , were evaluated. All patients received the same anesthesia regimen. At the end of operation patients were assessed for postoperative nausea and vomiting at post anesthesia care unit. Findings: Nausea was significantly lower in smokers in comparion with nonsmokers (32% vs. 64% and p=0.02). Vomiting was also significantly lower in smokers compared to nonsmokers (36% vs. 68% and p= 0.02). Also smoker patients above 30 years old significantly had lower incidence of vomiting in comparison with nonsmokers, and pethidine (20-25 mg) had more emetic effect in nonsmokers. Conclusion: The risk of postoperative nausea and vomiting (PONV) is reduced in cigarette smokers by unknown mechanisms. Keywords: cigarette smoking, nonsmoking, nausea and vomiting.